Building aggregate timber supply models from individual harvest choice

Timber supply has traditionally been modelled using aggregate data. In this paper, we build aggregate supply models for four roundwood products for the US state of North Carolina from a stand-level harvest choice model applied to detailed forest inventory. The simulated elasticities of pulpwood supply are much lower than reported by previous studies. Cross price elasticities indicate a dominant influence of sawtimber markets on pulpwood supply. This approach allows predicting the supply consequences of exogenous factors and supports regular updating of supply models.Timber supply, harvest choice, conditional logit, elasticity, expectations, simulation.,

Long Term Culture of Hepatocytes of Some Fish Species of the Chesapeake Bay

The liver is an important site of metabolism and effects of toxic chemicals. This makes it an important organ for tumorigenesis studies. This study was aimed at investigating the optimal culture characteristics of liver cells derived from some indigenous Chesapeake Bay fish species. Hepatocytes from Atlantic -menhaden (Brevootia tyraMus), toadfish (Opsanus tau), croaker (Micropogonius undulatus), and hogchocker (Trinectes maculatus) were isolated using an enzymatic dispersion technique. The highest yield was obtained from toadfish livers (14.9±5. lx 1 o5 cells/g oflive weight) and the lowest was from the croaker (5.9±3. lx 1 o5 cells/g of live body weight). The percentage of hepatocytes in cell preparations exceeded 90% except for the toadfish liver cells preparation (82.3%). Freshly isolated hepatocytes were globular with irregular contour and occurred as individual cells or small clusters of 2-30 cells. A confluent monolayer of attached cells was obtained after two weeks of incubation. An osmolality of 325 m Osm/kg best supported the multiplication of hepatocytes of the four fish species. While the optimum temperature for hogchocker and toadfish hepatocytes appeared to be 33oC; it ranged from 21-27oC for menhaden and croaker. The medium that best supported the growth of culture The potential of long term hepatocyte culture using fish of Chesapeake Bay will enable further studies on the activation and detoxification processes of xenobiotics and, therefore, help in understanding pollution related neoplasia and diseaseshttps://scholarworks.wm.edu/vimsbooks/1181/thumbnail.jp

Behavioural effects of pheromone-based control system, ExosexTM SPTab, on male Indianmeal moth, Plodia interpunctella

We report on laboratory studies to examine behavioural effects of a new pheromone-based control system for stored product moths, Exosex™ SPTab auto-confusion, on virgin male Plodia interpunctella. The SPTab comprises a compressed electrostatic powder tablet, containing the female sex pheromone (Z,E)-9,12-Tetradecadienyl acetate; designed to be an attractive source to males and disrupt the mate finding ability of several stored moth pest species. Our aims were to examine the effects of SPTab contact on male ability to locate females and to be attractive sources to other males. Observations of behavioural effects were made in a moth flight tunnel. Virgin male P. interpunctella were treated on SPTabs weathered from 1-8 weeks. After treatment, males were either immediately released downwind of calling females in the upwind section of the flight tunnel, or caged individually for 1 to 48 h before release. The ability of treated males to act as false lures for other males was measured by treating males on different age SPTabs as before, caging them and then placing them upwind of untreated males. In all studies males were scored on making source contact. Males treated on the SPTab and immediately released downwind of calling females showed a 96.7% reduction in their ability to contact the females. Males held for 48 h before release still showed a significant reduction in source contact compared to untreated controls. Treated males tested after 3 h, were as attractive as calling females with >75% of flights resulting in source contact. Significant reduction in female source contact was still evident when males were treated on SPTab weathered for 4 weeks. Males treated on SPTabs weathered for up to 8 weeks were significantly attractive to untreated males, and equal to calling females. The results indicate that contact with SPTab significantly reduces the ability of male P. interpunctella to locate females for up to two days. These males could increase the confusion effect by becoming competitive attractive point sources for other males. The Exosex SPTab has novel methods of causing mating disruption. Keywords: Mating disruption, Plodia interpunctella, Exosex SPTab, Sex pheromone, Flight tunnel

Zeno’s paradox in decision making

Classical probability theory has been influential in modeling decision processes, despite empirical findings that have been persistently paradoxical from classical perspectives. For such findings, some researchers have been successfully pursuing decision models based on quantum theory. One unique feature of quantum theory is the collapse postulate, which entails that measurements (or in decision making, judgments) reset the state to be consistent with the measured outcome. If there is quantum structure in cognition, then there has to be evidence for the collapse postulate. A striking, a priori prediction, is that opinion change will be slowed down (under idealized conditions frozen) by continuous judgments. In physics, this is the quantum Zeno effect. We demonstrate a quantum Zeno effect in decision making in humans and so provide evidence that advocates the use of quantum principles in decision theory, at least in some cases

The Gibbs paradox, Black hole entropy and the thermodynamics of isolated horizons

This letter presents a new, solely thermodynamical argument for considering the states of the quantum isolated horizon of a black hole as distinguishable. We claim that only if the states are distinguishable, the thermodynamic entropy is an extensive quantity and can be well-defined. To show this, we make a comparison with a classical ideal gas system whose statistical description makes only sense if an additional 1/N!-factor is included in the state counting in order to cure the Gibbs paradox. The case of the statistical description of a quantum isolated horizon is elaborated, to make the claim evident.Comment: 8 pages, closest to the published version; taken from the author's diploma thesi

Assessing the accuracy of quantitative molecular microbial profiling

This is the final version of the article. Available from MDPI via the DOI in this record.The application of high-throughput sequencing in profiling microbial communities is providing an unprecedented ability to investigate microbiomes. Such studies typically apply one of two methods: amplicon sequencing using PCR to target a conserved orthologous sequence (typically the 16S ribosomal RNA gene) or whole (meta)genome sequencing (WGS). Both methods have been used to catalog the microbial taxa present in a sample and quantify their respective abundances. However, a comparison of the inherent precision or bias of the different sequencing approaches has not been performed. We previously developed a metagenomic control material (MCM) to investigate error when performing different sequencing strategies. Amplicon sequencing using four different primer strategies and two 16S rRNA regions was examined (Roche 454 Junior) and compared to WGS (Illumina HiSeq). All sequencing methods generally performed comparably and in good agreement with organism specific digital PCR (dPCR); WGS notably demonstrated very high precision. Where discrepancies between relative abundances occurred they tended to differ by less than twofold. Our findings suggest that when alternative sequencing approaches are used for microbial molecular profiling they can perform with good reproducibility, but care should be taken when comparing small differences between distinct methods. This work provides a foundation for future work comparing relative differences between samples and the impact of extraction methods. We also highlight the value of control materials when conducting microbial profiling studies to benchmark methods and set appropriate thresholds.The authors acknowledge funding from the European Metrology Research Programme joint research project “INFECT MET” (http://infectmet.lgcgroup.com) (an EMRP project, jointly funded by the EMRP participating countries within EURAMET and the European Union) and the UK National Measurement System for funding of this work and for the support of Thomas Laver by the BBSRC Industrial Case Studentship award BB/H016120/1

Labels for non-individuals

Quasi-set theory is a first order theory without identity, which allows us to cope with non-individuals in a sense. A weaker equivalence relation called ``indistinguishability'' is an extension of identity in the sense that if $x$ is identical to $y$ then $x$ and $y$ are indistinguishable, although the reciprocal is not always valid. The interesting point is that quasi-set theory provides us a useful mathematical background for dealing with collections of indistinguishable elementary quantum particles. In the present paper, however, we show that even in quasi-set theory it is possible to label objects that are considered as non-individuals. We intend to prove that individuality has nothing to do with any labelling process at all, as suggested by some authors. We discuss the physical interpretation of our results.Comment: 11 pages, no figure

Transport behavior of holes in boron delta-doped diamond structures

Boron delta-doped diamond structures have been synthesized using microwave plasma chemical vapor deposition and fabricated into FET and gated Hall bar devices for assessment of the electrical characteristics. A detailed study of variable temperature Hall, conductivity, and field-effect mobility measurements was completed. This was supported by Schr€dinger-Poisson and relaxation time o calculations based upon application of Fermi’s golden rule. A two carrier-type model was developed with an activation energy of $0.2 eV between the delta layer lowest subband with mobility$1 cm2/Vs and the bulk valence band with high mobility. This new understanding of the transport of holes in such boron delta-doped structures has shown that although Hall mobility as high as 900 cm2/Vs was measured at room temperature, this dramatically overstates the actual useful performance of the device

Space as a low-temperature regime of graphs

I define a statistical model of graphs in which 2-dimensional spaces arise at low temperature. The configurations are given by graphs with a fixed number of edges and the Hamiltonian is a simple, local function of the graphs. Simulations show that there is a transition between a low-temperature regime in which the graphs form triangulations of 2-dimensional surfaces and a high-temperature regime, where the surfaces disappear. I use data for the specific heat and other observables to discuss whether this is a phase transition. The surface states are analyzed with regard to topology and defects.Comment: 22 pages, 12 figures; v3: published version; J.Stat.Phys. 201

Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: an inter-laboratory study.

Antimicrobial resistance (AMR) poses a threat to public health. Clinical microbiology laboratories typically rely on culturing bacteria for antimicrobial-susceptibility testing (AST). As the implementation costs and technical barriers fall, whole-genome sequencing (WGS) has emerged as a 'one-stop' test for epidemiological and predictive AST results. Few published comparisons exist for the myriad analytical pipelines used for predicting AMR. To address this, we performed an inter-laboratory study providing sets of participating researchers with identical short-read WGS data from clinical isolates, allowing us to assess the reproducibility of the bioinformatic prediction of AMR between participants, and identify problem cases and factors that lead to discordant results. We produced ten WGS datasets of varying quality from cultured carbapenem-resistant organisms obtained from clinical samples sequenced on either an Illumina NextSeq or HiSeq instrument. Nine participating teams ('participants') were provided these sequence data without any other contextual information. Each participant used their choice of pipeline to determine the species, the presence of resistance-associated genes, and to predict susceptibility or resistance to amikacin, gentamicin, ciprofloxacin and cefotaxime. We found participants predicted different numbers of AMR-associated genes and different gene variants from the same clinical samples. The quality of the sequence data, choice of bioinformatic pipeline and interpretation of the results all contributed to discordance between participants. Although much of the inaccurate gene variant annotation did not affect genotypic resistance predictions, we observed low specificity when compared to phenotypic AST results, but this improved in samples with higher read depths. Had the results been used to predict AST and guide treatment, a different antibiotic would have been recommended for each isolate by at least one participant. These challenges, at the final analytical stage of using WGS to predict AMR, suggest the need for refinements when using this technology in clinical settings. Comprehensive public resistance sequence databases, full recommendations on sequence data quality and standardization in the comparisons between genotype and resistance phenotypes will all play a fundamental role in the successful implementation of AST prediction using WGS in clinical microbiology laboratories